Estresse e ansiedade em mulheres submetidas à reprodução humana assistida

Abstract

Many women express concerns and interests about reproductive functioning. Not all of them get their child through natural reproduction yet, and with that, they need to resort to assisted reproduction treatments, which can be a stressor for many of them. The aim of the study was to investigate and compare the levels of stress and anxiety in women undergoing Assisted Human Reproduction Treatment (TRHA) before and after in vitro fertilization (IVF); as well as raising sociodemographic and clinical characteristics; verify correlation of stress and anxiety in maturity and oocyte quality and in the final result; compare stress and anxiety before and after the procedure. It is a descriptive, longitudinal research. The participants answered the Sociodemographic Questionnaire, the Beck Anxiety Inventory (BAI) and the Lipp Stress Symptoms Inventory (ISSL). 26 women participated in the study. The mean age was 31.5 years (± 2.54); married, with an average of 3.5 years of natural pregnancy attempts (± 2.57). Of the sample, fourteen (53.84%) had a female factor as impeding factor, six (23.07%) male factor, three (11.53%) female factor plus male factor, and three (11.53%) without cause apparent. The results from BAI indicated that twenty (76.93%) did not present pre treatment anxiety symptoms, three (11.53%) mild anxiety, one (3.85%) moderate and two (7.69%) severe. In the post-treatment period, twenty (76.93%) showed no anxiety and six (23.07%) mild. The ISSL results indicated that twenty (76.93%) had no pre-treatment stress and six (23.07%) in the resistance phase. In the post-treatment period, twenty-one (80.77%) had no stress and five (19.23%) had it in the resistance phase. Regarding the laboratory report, the median of captured oocytes was 15 (range 3 to 41); mature oocytes (MII) of 11 (range 3 to 28); immature oocytes (MI) 0.9 (range 0 to 5); immature oocytes (PI) 0.7 (range 0 to 5), and ruptured oocytes 0.6 (range 0 to 6). Beta HCG was seventeen (65.38%) positive and nine (34.61%) negative. Conclusions: The study participants did not show significant symptoms of stress and anxiety. Regarding anxiety, there was no correlation between pre- and post-treatment symptoms with oocyte quality and final result (Beta HCG). In relation to stress, it was already possible to identify that twenty of the participants (76.93%) had no symptoms of stress in the pre and post treatment and, thus, influenced the oocyte quality (p = 0.0027) in the MII stage, however in relation to Beta HCG did not correlate with stress symptoms.