Tratamento de tuberculose latente: um desafio para o controle da doença

Abstract

early detection of latent tuberculosis infection is one of the TB control strategy recommended by the World Health Organization. Objective: to analyze the association of latent tuberculosis infection with sociodemographic, clinical and risk factors for active TB cases chemoprophylaxis. Material and Methods: A retrospective cross-sectional epidemiological study, based on secondary data chemoprophylaxis notification form of tuberculosis of the state information system (TBWEB) of Epidemiological Surveillance Group XXIX (GVE 29) of São José do Rio Preto. They considered all reported cases from 2009 to 2013. The selected variables were sociodemographic and clinical. For the analysis, all statistical tests were applied with a 0.05 significance level. The software used for analysis were Minitab® 17 (Minitab Inc.) and Statistica 10 (StatSoft Inc.). Results: predominance of females, mean age 37.51 years and median of 40.00 years. Smear the day with negative sputum was associated significantly with cough (P = 0.001) and occupation (P <0.001). Few HIV / AIDS and health care professionals made the smear and sputum culture. Conclusion: The study found it hard both in screening latent tuberculosis, as in diagnosis and treatment, which may contribute to the spread of TB and multidrug resistance, increasing the morbidity and mortality rates from the disease, particularly among co-infected with HIV.